The Spatial Information Architecture Laboratory (SIAL) is a facility for innovation in transdisciplinary design research and education. It embraces a broad range of investigative modes, involving both highly speculative and industry linked projects. SIAL is concerned with the integration of technical, theoretical and social concerns as part of its innovation agenda. High-end computing, modelling and communication tools associated with disparate disciplines are combined with traditional production techniques. Researchers are engaged in a wide variety of projects that collaboratively disturb artificial distinctions between the physical and virtual, digital and analogue, scientific and artistic, instrumental and philosophical.